Over four centuries ago, William Shakespeare collaborated with others on a play about the historical figure Sir Thomas More. In it, he wrote a speech in which More passionately articulates a defence of refugees, culminating in a poignant reference to their plight. Fast-forward to the present: Aleppo, in the midst of the Syrian civil war. Amira, a paediatric surgeon, performs a life-saving operation during the darkest days of the conflict. Through an unexpected twist of fate, she and her daughter become central characters in a dangerous tale that intricately interweaves the lives of five families spanning four continents and redefines all of their existences. Versions of this story continue to repeat themselves over the centuries. For this reason, Shakespeare aptly named this plight “The Strangers’ Case”.